PLF is a healthcare transformation model that aligns care systems with the physical laws that govern biological life—from atoms and molecules to entire organs and systems. It seeks to deliver more effective and equitable healthcare by working with, not against, the body’s natural processes.

Current healthcare systems often violate the fundamental laws of biology—through delays, fragmented care, and systemic inequities—which can worsen outcomes. PLF offers a science-based framework to prevent and reverse these problems by restoring biological order.

PLF tackles systemic disorder in healthcare: late diagnoses, access delays, fragmented records, and care decisions that ignore biology's timing or energy needs. These violations disproportionately affect marginalized communities.

• Conservation of Biological Order

• Energetic Efficiency

• Information Transfer Fidelity

• Temporal Alignment

• Equilibrium Restoration

• Environmental Foundation Integrity

PLF directly addresses health disparities by showing that poor outcomes are often the result of systemic violations of biological law—such as access barriers, environmental stress, or poor coordination—not individual failings. By realigning care, PLF reduces inequities.

It’s a scientific framework for organizing both policy and practice. PLF can inform how we design benefits, deliver care, set quality measures, and engage communities—all grounded in physics and biology

The National Minority Quality Forum (NMQF) developed the PLF to advance systems that deliver equitable, biology-aligned care. It serves as the foundation of NMQF’s research, advocacy, and policy efforts.